Pharmacists, patients may have questions when they pick up their prescription of Ozempic®. Here are some topics you may want to discuss with them.
Talking to your patients about Ozempic®


Ozempic® 1 mg is now available in a 4-dose pen
Ozempic® 1 mg is now available in a 4-dose pen

What is Ozempic®?
- Ozempic® is a once-weekly human glucagon-like peptide-1 (GLP-1) receptor agonist
- Ozempic® is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus and to reduce the risk of major adverse cardiovascular (CV) events (CV death, nonfatal myocardial infarction, or nonfatal stroke) in adults with type 2 diabetes mellitus and established CV disease


Limitations of Use
- Ozempic® has not been studied in patients with a history of pancreatitis. Consider other antidiabetic therapies in patients with a history of pancreatitis.
- Ozempic® is not a substitute for insulin. Ozempic® is not indicated for use in patients with type 1 diabetes mellitus or for the treatment of patients with diabetic ketoacidosis.
Once-weekly dosing designed with patients in mind1
Gradual dose escalation designed to help patients adjust to therapya








aThe starting dose of 0.25 mg is a nontherapeutic dose intended to help patients adjust to treatment.
- Administer Ozempic® once weekly on the same day each week, at any time of the day, with or without meals
- The day of weekly administration can be changed if necessary as long as the time between 2 doses is at least 2 days (>48 hours)
- If a dose is missed, administer Ozempic® as soon as possible within 5 days after the missed dose. If more than 5 days have passed, skip the missed dose and administer the next dose on the regularly scheduled day. In each case, patients can then resume their regular once-weekly dosing schedule
Ozempic® is available in multiuse pens with needles included1
The Ozempic® injection is supplied as a clear, colorless solution in a prefilled, disposable, single-patient-use pen in the following packaging configurations:
Red-label pen only delivers the starting dose of 0.25 mg and a maintenance dose of 0.5 mg1

Contains 2 mg of Ozempic® in a 1.5 mL pen
Blue-label pen only delivers the maximum maintenance dose of 1 mg1

Contains 4 mg of Ozempic® in a 3 mL pen

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Help your patients understand the Ozempic® 1 mg pen update
If you have patients taking the maximum 1 mg dose of Ozempic®, you can download and print this tear pad to help them understand what’s different about their pen starting in April 2021.1
Order today
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Ozempic® demo pen
Demonstration Pen (0.25 mg, 0.5 mg): For demonstration and training only. Not for patients or injection into humans. Does not contain medicine. Only to be used by a health care professional. Needles are not included.
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Ozempic® Pen Instructions For Use
Help your patients learn how to use the Ozempic® Pen with this easy-to-follow video that illustrates how they can administer Ozempic®.
Direct your patients to text PEN to 43967 to get a link to the video.
How to store the Ozempic® Pen1
Prior to first use
Until expiration date
Refrigerated
36°F to 46°F (2°C to 8°C)

Refrigerated
36°F to 46°F (2°C to 8°C)
Refrigerated
36°F to 46°F (2°C to 8°C)
After first use
56 days
Room Temperature
59°F to 86°F (15°C to 30°C)

Room Temperature
59°F to 86°F (15°C to 30°C)
Refrigerated
36°F to 46°F (2°C to 8°C)

Refrigerated
36°F to 46°F (2°C to 8°C)

How to dispense Ozempic®

Ozempic® 0.25 mg or 0.5 mg dose
(2 mg/1.5 mL subcutaneous pen injector)

NDC: 0169-4132-12
Days supply:
• Sample/initial (42 days)
• 1-month supply (28 days)
Intent of prescription:
• Sample or initial prescription for new starts
• 1-month prescription for maintenance on 0.5 mg
Strength: 2 mg per 1.5 mL (1.34 mg/mL)
Dosage form: Solution
SIG:
• Sample or initial Rx: 0.25 mg SC once weekly for 4 weeks, then 0.5 mg SC once weekly for 2 weeks
• Maintenance Rx: 0.5 mg SC once weekly
Dispense quantity: 1.5 mL
Dispense quantity unit of measure: mL ONLY
Needles: 6 included
Number of boxes: 1 box
Ozempic® 1 mg dose
(4 mg/3 mL subcutaneous pen injector)

NDC: 0169-4130-13
Days supply:
1-month supply (28 days)
Intent of prescription:
1-month prescription for maintenance on 1 mg
Strength: 4 mg per 3 mL (1.34 mg/mL)
Dosage form: Solution
SIG:
Maintenance Rx: 1 mg SC once weekly
Dispense quantity: 3 mL
Dispense quantity unit of measure: mL ONLY
Needles: 4 included
Number of boxes: 1 box

Ozempic® 0.25 mg or 0.5 mg dose
(2 mg/1.5 mL subcutaneous pen injector)

NDC: 0169-4132-12
Days supply:
3-month supply (84 days)
Intent of prescription:
3-month prescription for maintenance on 0.5 mg
Strength: 2 mg per 1.5 mL (1.34 mg/mL)
Dosage form: Solution
SIG: Maintenance Rx: Inject 0.5 mg SC once weekly for 12 weeks
Dispense quantity: 4.5 mL
Dispense quantity unit of measure: mL ONLY
Needles: 18 included
Number of boxes: 3 boxes
Ozempic® 1 mg dose
(4 mg/3 mL subcutaneous pen injector)

NDC: 0169-4130-13
Days supply:
3-month supply (84 days)
Intent of prescription:
3-month prescription for maintenance on 1 mg
Strength: 4 mg per 3 mL (1.34 mg/mL)
Dosage form: Solution
SIG: Maintenance Rx: Inject 1 mg SC once weekly for 12 weeks
Dispense quantity: 9 mL
Dispense quantity unit of measure: mL ONLY
Needles: 12 included
Number of boxes: 3 boxes

1-month supply (28 days)
Ozempic® 0.25 mg or 0.5 mg dose
(2 mg/1.5 mL subcutaneous pen injector)

NDC: 0169-4132-12
Days supply:
• Sample/initial (42 days)
• 1-month supply (28 days)
Intent of prescription:
• Sample or initial prescription for new starts
• 1-month prescription for maintenance on 0.5 mg
Strength: 2 mg per 1.5 mL (1.34 mg/mL)
Dosage form: Solution
SIG:
• Sample or initial Rx: 0.25 mg SC once weekly for 4 weeks, then 0.5 mg SC once weekly for 2 weeks
• Maintenance Rx: 0.5 mg SC once weekly
Dispense quantity: 1.5 mL
Dispense quantity unit of measure: mL ONLY
Needles: 6 included
Number of boxes: 1 box
3-month supply (84 days)
Ozempic® 0.25 mg or 0.5 mg dose
(2 mg/1.5 mL subcutaneous pen injector)

NDC: 0169-4132-12
Days supply:
3-month supply (84 days)
Intent of prescription:
3-month prescription for maintenance on 0.5 mg
Strength: 2 mg per 1.5 mL (1.34 mg/mL)
Dosage form: Solution
SIG: Maintenance Rx: Inject 0.5 mg SC once weekly for 12 weeks
Dispense quantity: 4.5 mL
Dispense quantity unit of measure: mL ONLY
Needles: 18 included
Number of boxes: 3 boxes
1-month supply (28 days)
Ozempic® 1 mg dose
(4 mg/3 mL subcutaneous pen injector)

NDC: 0169-4130-13
Days supply:
1-month supply (28 days)
Intent of prescription:
1-month prescription for maintenance on 1 mg
Strength: 4 mg per 3 mL (1.34 mg/mL)
Dosage form: Solution
SIG:
Maintenance Rx: 1 mg SC once weekly
Dispense quantity: 3 mL
Dispense quantity unit of measure: mL ONLY
Needles: 4 included
Number of boxes: 1 box
3-month supply (84 days)
Ozempic® 1 mg dose
(4 mg/3 mL subcutaneous pen injector)

NDC: 0169-4130-13
Days supply:
3-month supply (84 days)
Intent of prescription:
3-month prescription for maintenance on 1 mg
Strength: 4 mg per 3 mL (1.34 mg/mL)
Dosage form: Solution
SIG: Maintenance Rx: Inject 1 mg SC once weekly for 12 weeks
Dispense quantity: 9 mL
Dispense quantity unit of measure: mL ONLY
Needles: 12 included
Number of boxes: 3 boxes