Ozempic® reduces blood glucose through a mechanism where it stimulates insulin secretion and lowers glucagon secretion, both in a glucose-dependent manner. The mechanism of blood glucose lowering also involves a minor delay in gastric emptying in the early postprandial phase.1
Once-weekly Ozempic® mechanism of action
Ozempic® delivers week-long coverage1
~7 days | Elimination half-life of ~7 days.
4 to 5 weeks
Steady-state plasma concentrations achieved following 4 to 5 weeks of once-weekly administration.
Ozempic® is dosed once weekly
Ozempic® has gradual dose escalation designed to help patients adjust to therapy.1,a Patients should administer Ozempic® once weekly with or without meals.
Pen shown delivers 0.25 mg or 0.5 mg per injection.